DuoNeb is an inhalation solution that combines the active ingredients ipratropium and albuterol. These two ingredients are bronchodilators that relax the muscles in the airways, improving airflow to your lungs. This inhalation solution is used to prevent bronchospasms in patients suffering from chronic obstructive pulmonary disease (COPD). DuoNeb is typically prescribed to those who are using other medicines to control their COPD symptoms. Overusing DuoNeb may result in death. Only use the prescribed dose of this medicine.

Please refer to the medication’s leaflet for information before using this inhalation solution.

Always follow your doctor’s instructions.

• Use this solution with a nebulizer
• Open the foil pouch
• Remove one vial
• Empty medicine into the chamber of the nebulizer
• Attach mouthpiece and attach the drug chamber to the compressor
• Place the mouthpiece in your mouth and turn on the compressor
• Sit upright throughout
• Inhale slowly and evenly until the drug chamber is empty
• Clean nebulizer after use

Do not use DuoNeb if you are allergic to albuterol, ipratropium, or atropine. Also, tell your doctor if you have one or more of the following conditions to ensure DuoNeb is safe for you.

• Coronary artery disease
• Glaucoma
• Epilepsy
• Liver disease
• Overactive thyroid
• Heart rhythm disorder
• Kidney disease
• Heart disease
• High blood pressure
• Diabetes
• An enlarged prostate

DuoNeb is not approved for use by those who are under the age of 18.

Common side effects of DuoNeb include:

• Headache
• Difficulty breathing
• Cold symptoms

Contact your doctor right away if you experience a severe side effect, such as:

• Wheezing
• Choking
• Chest pain
• Increased heart rate
• Tremors
• Nervousness
• Swelling in the ankles or feet
• Blurred vision
• Tunnel vision
• Eye pain
• Urination pain
• Leg cramps, constipation, numbness, or other signs of low potassium

What are some drug interactions for DuoNeb?

Many over-the-counter or prescription medicines, vitamins, and herbal products may interact with DuoNeb, so it is important to inform your doctor about all of the medications you are taking. The most common drug interactions for DuoNeb include diuretics, heart or blood pressure medicines, beta-blockers, and antidepressants. Ask your doctor for a complete list of drug interactions for DuoNeb.

Can DuoNeb be used while I am pregnant or when I am breastfeeding?

DuoNeb should not be used during pregnancy unless your doctor specifically tells you that it is safe. You should discuss if the benefits of DuoNeb outweigh the risk to the fetus with your doctor. It is unknown whether ipratropium and albuterol are excreted into breast milk.